Publication Date 01/02/2012         Volume. 2012 No. 1   
Information to Pharmacists

Editorial

From the desk of the editor

Welcome to the first homepage edition of i2P for 2012.
In many ways it has been a slow start to the New Year because of having to deal with the “leftovers” from 2011.
One of those items for i2P was that a third-party provider to the site did not advise of a code change to the security section in our subscribe panel, creating a range of frustrated subscribers not able to get on board.
We apologise to all those potential subscribers who were unable to register with us in the second half of 2011, but if you try once more you should have no problem.

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Antioxidants do not increase Melanoma risk

Staff Writer

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Editing and Researching news and stories about global and local Pharmacy Issues

Antioxidant Supplementation and Risk of Incident Melanomas

 Results of a Large Prospective Cohort Study

http://archderm.ama-assn.org/cgi/content/short/145/8/879?home 

 Maryam M. Asgari, MD, MPH; Sonia S. Maruti, MSc, ScD; Lawrence H. Kushi, ScD; Emily White, PhD

Arch Dermatol. 2009;145(8):879-882.

Vitamin and mineral supplements containing antioxidants are not associated with an increased melanoma risk, according to new research published in the Archives of Dermatology.

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Recently published data from the Supplementation in Vitamins and Mineral Antioxidants (SUVIMAX) study, reported a 4-fold higher melanoma risk in women randomized to receive a supplement with nutritionally appropriate doses of antioxidants.

A new study was undertaken to investigate these findings. 

The new study included a total of 69 671 men and women who self-reported:
(1) intake of multivitamins and supplemental antioxidants, including selenium and beta carotene, during the past 10 years and
(2) melanoma risk factors on a baseline questionnaire.

Cox proportional hazards regression models were used to estimate multivariable relative risks (RRs) and 95% confidence intervals (CIs) for multivitamin, supplemental selenium, and supplemental beta carotene use. After adjusting for melanoma risk factors, no significant association between multivitamin use and melanoma risk were detected in women (RR, 1.14; 95% CI, 0.78-1.66) or in men (RR, 1.09; 95% CI, 0.83-1.43). No increased melanoma risk with the use of supplemental beta carotene (RR, 0.87; 95% CI, 0.48-1.56) or selenium (RR, 0.98; 95% CI, 0.69-1.41) was observed at doses comparable with those of the SUVIMAX study.

 

Conclusion Antioxidants taken in nutritional doses do not seem to increase melanoma risk.

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